DDX6P2

Across TCGA pan-cancer cohorts, DDX6P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of DDX6P2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DDX6P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DDX6P2 is over-expressed in tumor, although a few such as ESCA and KIRC show the opposite, repressed pattern.

HNSC, COAD, and ESCA are the cancer types where DDX6P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DDX6P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.024	.011	5	view →
COAD	Female	III,IV	+0.086	.014	4	view →
ESCA	All	II,III,IV	−0.079	.007	2	view →
KICH	Female	II,III,IV	+0.040	.015	1	view →
KIRC	Male	III,IV	−0.017	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

DDX6P2–HNSC

Open the HNSC breakdown →