DDX60L

Across TCGA cell cohorts, DDX60L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,998 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DDX60L-associated GO terms across cancer lineages are Intracellular receptor signaling pathway, Positive regulation of protein binding, and Negative regulation of viral genome replication. Each is linked with DDX60L in more than 15 cancer types. Because this analysis shows association rather than direction, both DDX60L-to-partner and partner-to-DDX60L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular receptor signaling pathway grouped by DDX60L-low versus DDX60L-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX60L→partner) and Y-score (partner→DDX60L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Intracellular receptor signaling pathway →	+0.052	+1.381	.002	.001	3	16
LUNG_NSCLC_LUSC	Positive regulation of protein binding →	+0.152	+1.885	.001	.002	3	16
BREAST	Negative regulation of viral genome replication →	+0.205	+2.009	<.001	<.001	3	16
BONE	Regulation of proteolysis →	+0.139	+1.909	<.001	<.001	3	16
LIVER	Maintenance of protein location in cell →	+0.126	+1.423	<.001	<.001	3	15
LIVER	Maintenance of protein location →	+0.127	+1.423	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,998 associations by consensus.

Intracellular receptor signaling pathway by DDX60L expression — OVARY

Explore this box plot interactively →