DDX60L

Across TCGA cell cohorts, DDX60L mutation is significantly associated with the RNA expression of many other genes, with 1,179 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX60L-associated genes across cancer lineages are EFCAB9, KLF14, and HINT2. Each is linked with DDX60L in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX60L-to-partner and partner-to-DDX60L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EFCAB9 grouped by DDX60L-low versus DDX60L-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX60L→partner) and Y-score (partner→DDX60L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	EFCAB9 →	+0.066	+3.256	<.001	.005	3	3
BLOOD_Leukemia	KLF14 →	+0.059	+3.469	<.001	.004	3	2
LARGE_INTESTINE	HINT2 →	+0.492	+3.169	.009	.009	3	2
LARGE_INTESTINE	NGLY1 →	+0.364	+3.386	.003	.001	3	2
LARGE_INTESTINE	ACER1 →	+0.060	+2.131	.002	.001	3	2
LARGE_INTESTINE	RPL4 →	+0.440	+2.743	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,179 associations by consensus.

EFCAB9 by DDX60L expression — LUNG_SCLC

Explore this box plot interactively →