DDX59

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DDX59 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,681 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX59-associated proteins across cancer lineages are BROX, C1orf35, and GATAD2B. Each is linked with DDX59 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDX59-to-partner and partner-to-DDX59 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX59 versus BROX in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX59→partner) and Y-score (partner→DDX59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCBROX →+0.452+0.557<.001<.00138
GBMC1orf35 →+0.530+0.332<.001<.00136
UCECGATAD2B →+0.335+0.596<.001<.00136
LSCCIPO9 →+0.322+0.472<.001<.00136
LSCCIRF2BP2 →+0.262+0.470<.001<.00136
UCECRO60 →+0.355+0.541<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,681 associations by consensus.

DDX59 vs BROX — LSCC

Per-sample scatter of DDX59 vs BROX in LSCC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration