DDX58

Across TCGA patient cohorts, DDX58 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,517 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DDX58-associated proteins across cancer lineages are OAS2, OAS3, and PARP14. Each is linked with DDX58 in more than 9 cancer types. Because this analysis shows association rather than direction, both DDX58-to-partner and partner-to-DDX58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX58 versus OAS2 in UCEC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX58→partner) and Y-score (partner→DDX58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OAS2 →	+0.900	+0.672	<.001	<.001	3	10
OV	OAS3 →	+0.785	+1.211	<.001	<.001	3	10
OV	PARP14 →	+0.430	+1.130	<.001	<.001	3	10
HNSC	IFIH1 →	+0.854	+1.497	<.001	<.001	3	10
GBM	IFIH1_S301 →	+1.008	+1.017	<.001	<.001	3	10
HNSC	IFIT1 →	+1.149	+1.365	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,517 associations by consensus.

DDX58 vs OAS2 — UCEC

Explore this scatter interactively →