DDX58

Across TCGA patient cohorts, DDX58 protein abundance is significantly associated with the RNA expression of many other genes, with 9,556 significant associations in total. OV shows the largest number of these associations.

The most reproducible DDX58-associated genes across cancer lineages are OAS3, OAS2, and IFIH1. Each is linked with DDX58 in more than 9 cancer types. Because this analysis shows association rather than direction, both DDX58-to-partner and partner-to-DDX58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX58 versus OAS3 in OV, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX58→partner) and Y-score (partner→DDX58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OAS3 →	+1.535	+0.802	<.001	<.001	3	10
OV	OAS2 →	+1.744	+0.834	<.001	<.001	3	10
HNSC	IFIH1 →	+1.300	+0.943	<.001	<.001	3	10
HNSC	IFIT3 →	+1.882	+0.829	<.001	<.001	3	10
GBM	XAF1 →	+1.290	+0.755	<.001	<.001	3	10
HNSC	RSAD2 →	+1.924	+0.987	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,556 associations by consensus.

DDX58 vs OAS3 — OV

Explore this scatter interactively →