DDX58

Across TCGA patient cohorts, DDX58 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,345 significant associations in total. OV shows the largest number of these associations.

The most reproducible DDX58-associated proteins across cancer lineages are CMPK2, SAMHD1, and SP110_S380. Each is linked with DDX58 in more than 9 cancer types. Because this analysis shows association rather than direction, both DDX58-to-partner and partner-to-DDX58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX58 versus CMPK2 in HNSC, with a Pearson correlation of 0.83.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX58→partner) and Y-score (partner→DDX58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CMPK2 →	+1.001	+1.024	<.001	<.001	3	10
HNSC	SAMHD1 →	+0.626	+0.905	<.001	<.001	3	10
GBM	SP110_S380 →	+0.711	+0.746	<.001	<.001	3	10
HNSC	STAT1 →	+0.705	+0.895	<.001	<.001	3	10
OV	TAP1 →	+0.591	+0.464	<.001	<.001	3	10
BRCA	TAP2 →	+1.052	+0.681	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,345 associations by consensus.

DDX58 vs CMPK2 — HNSC

Explore this scatter interactively →