DDX56

Across TCGA patient cohorts, DDX56 mutation is significantly associated with the RNA expression of many other genes, with 4,019 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX56-associated genes across cancer lineages are RNU6-166P, RN7SKP265, and RN7SL314P. Each is linked with DDX56 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX56-to-partner and partner-to-DDX56 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-166P grouped by DDX56-low versus DDX56-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX56→partner) and Y-score (partner→DDX56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-166P →	+0.243	+6.623	<.001	<.001	3	3
HNSC	RN7SKP265 →	+0.305	+5.654	<.001	<.001	3	3
SKCM	RN7SL314P →	+0.095	+5.039	.007	.003	3	3
HNSC	OR51T1 →	+0.029	+4.505	.001	.009	3	2
HNSC	RN7SKP72 →	+0.104	+4.822	<.001	.006	3	2
HNSC	MIR517A →	+0.267	+5.221	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,019 associations by consensus.

RNU6-166P by DDX56 expression — HNSC

Explore this box plot interactively →