DDX56

Across TCGA cell cohorts, DDX56 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,951 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DDX56-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, Nucleolar large rRNA transcription by RNA polymerase I, and Transcription initiation at RNA polymerase I promoter. Each is linked with DDX56 in more than 15 cancer types. Because this analysis shows association rather than direction, both DDX56-to-partner and partner-to-DDX56 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgG isotypes grouped by DDX56-low versus DDX56-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX56→partner) and Y-score (partner→DDX56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of isotype switching to IgG isotypes →	+0.124	+0.621	<.001	<.001	3	16
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.112	+0.646	<.001	<.001	3	14
SOFT_TISSUE	Transcription initiation at RNA polymerase I promoter →	+0.113	+0.795	<.001	<.001	3	14
BONE	rRNA metabolic process →	+0.141	+0.907	<.001	<.001	3	14
LARGE_INTESTINE	Transcription by RNA polymerase I →	+0.089	+0.441	.002	.002	3	13
BLOOD_Myeloma	rRNA transcription →	+0.132	+1.156	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,951 associations by consensus.

Positive regulation of isotype switching to IgG isotypes by DDX56 expression — PANCREAS

Explore this box plot interactively →