DDX56

Across TCGA cell cohorts, DDX56 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX56-associated genes across cancer lineages are GPR119, MRGPRE, and C3orf85. Each is linked with DDX56 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX56-to-partner and partner-to-DDX56 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR119 grouped by DDX56-low versus DDX56-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX56→partner) and Y-score (partner→DDX56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GPR119 →	+0.022	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	MRGPRE →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	C3orf85 →	+0.082	+4.867	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1L6 →	+0.019	+5.662	<.001	.002	3	1
LARGE_INTESTINE	MS4A4A →	+0.219	+3.678	<.001	.009	3	1
LARGE_INTESTINE	MSGN1 →	+0.100	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

GPR119 by DDX56 expression — BLOOD_Lymphoma

Explore this box plot interactively →