DDX52

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DDX52 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,691 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX52-associated GO terms across cancer lineages are Regulation of cell cycle G2/M phase transition, Epigenetic regulation of gene expression, and Nuclear pore organization. Each is linked with DDX52 in more than 14 cancer types. Because this analysis shows association rather than direction, both DDX52-to-partner and partner-to-DDX52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle G2/M phase transition grouped by DDX52-low versus DDX52-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX52→partner) and Y-score (partner→DDX52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASRegulation of cell cycle G2/M phase transition →+0.075+0.885<.001<.001315
LUNG_SCLCEpigenetic regulation of gene expression →+0.059+0.554<.001<.001314
BREASTNuclear pore organization →+0.116+0.927.001.001314
SOFT_TISSUENucleic acid transport →+0.102+0.804<.001<.001314
SOFT_TISSUERNA transport →+0.102+0.804<.001<.001314
LIVERDouble-strand break repair via alternative nonhomologous end joining →+0.169+0.863<.001.002313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

Regulation of cell cycle G2/M phase transition by DDX52 expression — PANCREAS

Box plot of Regulation of cell cycle G2/M phase transition in DDX52-low vs DDX52-high samples in PANCREAS.

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Exploration