Across TCGA pan-cancer cohorts, DDX51 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DDX51 data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher DDX51 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DDX51 expression acts as an unfavorable survival marker.

THYM, HNSC, and UVM are the cancer types where DDX51 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
HNSC	DFS	Median	IV	0.148	0.647	<.001	33	view →
UVM	DFS	Median	All	0.079	0.746	<.001	18	view →
BRCA	DFS	Median	All	0.745	0.949	.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	All	0.330	0.784	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: DDX51 tumor-vs-normal RNA expression · all DDX51 data types