DDX50P1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, DDX50P1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of DDX50P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where DDX50P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DDX50P1 is over-expressed in tumor.

COAD, HNSC, and BLCA are the cancer types where DDX50P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DDX50P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADFemaleII,III,IV+0.441<.00112view →
HNSCFemaleAll+0.162<.00111view →
BLCAAllAll+0.469<.00110view →
LUADMaleAll+0.424<.0016view →
LUSCAllAll+0.340<.0016view →
READMaleAll+0.286.0016view →
KIRCAllAll+0.094<.0016view →
STADAllII,III,IV+0.323<.0015view →
LIHCAllAll+0.056.0015view →
CHOLAllAll+0.564<.0014view →
BRCAAllII,III,IV+0.141.0034view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

DDX50P1–COAD

Tumor-vs-normal expression box plot for DDX50P1 RNA in COAD.

Open the COAD breakdown →

Exploration