DDX50

Across TCGA cell cohorts, DDX50 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,163 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX50-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, DNA strand elongation, and Spindle elongation. Each is linked with DDX50 in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX50-to-partner and partner-to-DDX50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by DDX50-low versus DDX50-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX50→partner) and Y-score (partner→DDX50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.120	+0.570	<.001	.002	3	19
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.126	+0.578	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Spindle elongation →	+0.274	+0.695	.001	.001	3	16
LIVER	Negative regulation of chromosome segregation →	+0.162	+1.179	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Single strand break repair →	+0.085	+1.057	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Mitochondrial DNA replication →	+0.152	+0.587	.005	.007	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,163 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by DDX50 expression — OESOPHAGUS

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