DDX49

Across TCGA patient cohorts, DDX49 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,667 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX49-associated proteins across cancer lineages are THOC1, GATAD2A, and WIZ. Each is linked with DDX49 in more than 6 cancer types. Because this analysis shows association rather than direction, both DDX49-to-partner and partner-to-DDX49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX49 versus THOC1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX49→partner) and Y-score (partner→DDX49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	THOC1 →	+0.308	+0.443	<.001	<.001	3	7
UCEC	GATAD2A →	+0.293	+1.132	<.001	.002	3	7
GBM	WIZ →	+0.333	+0.394	<.001	<.001	3	6
COAD	YJU2 →	+0.391	+0.417	.003	<.001	3	6
LSCC	ARMC6 →	+0.409	+0.631	<.001	<.001	3	6
LSCC	UPF1 →	+0.319	+0.781	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,667 associations by consensus.

DDX49 vs THOC1 — GBM

Explore this scatter interactively →