DDX49

Across TCGA patient cohorts, DDX49 protein abundance is significantly associated with the RNA expression of many other genes, with 18,814 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX49-associated genes across cancer lineages are WDR43, TPX2, and UBE2C. Each is linked with DDX49 in more than 6 cancer types. Because this analysis shows association rather than direction, both DDX49-to-partner and partner-to-DDX49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX49 versus WDR43 in LSCC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX49→partner) and Y-score (partner→DDX49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR43 →	+0.770	+0.471	<.001	<.001	3	7
UCEC	TPX2 →	+1.509	+0.304	<.001	<.001	3	7
LUAD	UBE2C →	+1.413	+0.195	<.001	.002	3	7
UCEC	MYBL2 →	+1.494	+0.298	<.001	.001	3	7
UCEC	CCDC150 →	+0.922	+0.323	<.001	<.001	3	7
LSCC	RPP40 →	+0.775	+0.354	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,814 associations by consensus.

DDX49 vs WDR43 — LSCC

Explore this scatter interactively →