DDX49

Across TCGA cell cohorts, DDX49 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,979 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DDX49-associated GO terms across cancer lineages are Inner mitochondrial membrane organization, Ribosomal large subunit biogenesis, and DNA-templated transcription initiation. Each is linked with DDX49 in more than 13 cancer types. Because this analysis shows association rather than direction, both DDX49-to-partner and partner-to-DDX49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Inner mitochondrial membrane organization grouped by DDX49-low versus DDX49-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX49→partner) and Y-score (partner→DDX49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Inner mitochondrial membrane organization →	+0.090	+0.693	<.001	.003	3	14
BONE	Ribosomal large subunit biogenesis →	+0.133	+0.563	.006	.007	3	13
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.067	+0.676	<.001	<.001	3	13
BONE	rRNA transcription →	+0.131	+0.487	.002	.009	3	13
SKIN	Termination of RNA polymerase III transcription →	+0.104	+0.688	<.001	.001	3	12
PANCREAS	Pseudouridine synthesis →	+0.092	+0.917	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,979 associations by consensus.

Inner mitochondrial membrane organization by DDX49 expression — OVARY

Explore this box plot interactively →