DDX47

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DDX47 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DDX47 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DDX47 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DDX47 expression acts as an unfavorable survival marker, although some lineages such as LSCC and OV show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where DDX47 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianAll0.7350.936<.001146view →
HNSCOSTertileAll0.7940.905.0226view →
LUADOSQuartileII,III,IV0.4011.000.0106view →
LSCCDFSMedianII,III,IV0.8210.550.0245view →
OVDFSMedianAll1.0000.580.0324view →
UCECDFSMedianIII,IV0.9040.445.0374view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration