DDX47

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DDX47 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX47-associated genes across cancer lineages are Akt, 14-3-3_epsilon, and AMPK_alpha. Each is linked with DDX47 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX47-to-partner and partner-to-DDX47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX47→partner) and Y-score (partner→DDX47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADAkt →-0.625-3.000.005.03532
COAD14-3-3_epsilon →+0.125+3.212.048.00932
UCECAMPK_alpha →-0.219-3.321.002.00932
COADCaspase-7-cleavedD198 →+1.444+3.178<.001.01023
UCECMEK1 →+0.350+2.222.010.01032
UCECMyosin-IIa_pS1943 →+0.171+1.428.027.02932
Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration