DDX43

Across TCGA patient cohorts, DDX43 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,839 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DDX43-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, Regulation of protein dephosphorylation, and Positive regulation of type I interferon production. Each is linked with DDX43 in more than 16 cancer types. Because this analysis shows association rather than direction, both DDX43-to-partner and partner-to-DDX43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by DDX43-low versus DDX43-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX43→partner) and Y-score (partner→DDX43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.072	+0.943	.004	<.001	3	16
DLBC	Regulation of protein dephosphorylation →	+0.061	+0.914	.005	<.001	1	17
DLBC	Positive regulation of type I interferon production →	+0.082	+0.757	.001	.001	3	15
SCLC	Cellular senescence →	+0.085	+1.173	<.001	<.001	2	16
ESCA	Protein autophosphorylation →	+0.069	+0.871	<.001	<.001	2	16
SCLC	Myeloid cell development →	+0.074	+0.867	<.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,839 associations by consensus.

Nuclear-transcribed mRNA catabolic process by DDX43 expression — ESCA

Explore this box plot interactively →