DDX43

Across TCGA patient cohorts, DDX43 protein abundance is significantly associated with the RNA expression of many other genes, with 8,997 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX43-associated genes across cancer lineages are RPS6P8, PEX14, and MINDY1. Each is linked with DDX43 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX43-to-partner and partner-to-DDX43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX43 versus RPS6P8 in LUAD, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX43→partner) and Y-score (partner→DDX43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS6P8 →	+1.137	+1.812	<.001	<.001	3	3
LUAD	PEX14 →	+0.749	+1.662	<.001	.002	3	2
LUAD	MINDY1 →	+0.777	+1.599	.005	.001	3	2
LSCC	TAS2R2P →	+0.325	+0.553	.009	.005	3	2
LUAD	LGALS8-AS1 →	+0.815	+1.443	.001	.006	3	2
LUAD	LINC00271 →	+1.000	+1.904	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,997 associations by consensus.

DDX43 vs RPS6P8 — LUAD

Explore this scatter interactively →