Across TCGA patient cohorts, DDX42 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,817 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX42-associated proteins across cancer lineages are XPO1, EIF4A3, and GTF3C2. Each is linked with DDX42 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDX42-to-partner and partner-to-DDX42 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX42→partner) and Y-score (partner→DDX42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XPO1 →	+0.295	+0.441	<.001	<.001	3	5
GBM	EIF4A3 →	+0.280	+0.281	<.001	<.001	3	5
HNSC	GTF3C2 →	+0.250	+0.637	.002	.008	2	6
HNSC	HDAC2 →	+0.296	+0.525	.002	.002	3	5
GBM	HNRNPLL →	+0.331	+0.398	<.001	<.001	3	5
LSCC	COIL →	+0.413	+0.383	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,817 associations by consensus.

Exploration

DDX42 survival (RNA) · tumor vs normal (RNA) · all DDX42 data types