Across TCGA patient cohorts, DDX42 protein abundance is significantly associated with the RNA expression of many other genes, with 16,862 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX42-associated genes across cancer lineages are BRIP1, NUP85, and PTRH2. Each is linked with DDX42 in more than 8 cancer types. Because this analysis shows association rather than direction, both DDX42-to-partner and partner-to-DDX42 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX42→partner) and Y-score (partner→DDX42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BRIP1 →	+0.873	+0.269	<.001	<.001	3	9
LUAD	NUP85 →	+0.561	+0.146	<.001	<.001	3	8
LSCC	PTRH2 →	+0.629	+0.243	<.001	<.001	3	8
OV	POLG2 →	+0.564	+0.334	<.001	<.001	3	8
BRCA	CCDC47 →	+0.589	+0.250	.004	.005	3	7
LSCC	EME1 →	+0.901	+0.295	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,862 associations by consensus.

Exploration

DDX42 survival (RNA) · tumor vs normal (RNA) · all DDX42 data types