Across TCGA patient cohorts, DDX42 mutation is significantly associated with the RNA expression of many other genes, with 2,918 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX42-associated genes across cancer lineages are MIR4713, LCE1D, and RNU1-20P. Each is linked with DDX42 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX42-to-partner and partner-to-DDX42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX42→partner) and Y-score (partner→DDX42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR4713 →	+0.437	+5.438	<.001	.002	3	3
STAD	LCE1D →	+0.230	+4.217	<.001	<.001	3	3
SKCM	RNU1-20P →	+0.180	+3.098	<.001	.008	3	3
BLCA	RNU6-1213P →	+0.201	+4.500	<.001	.004	3	2
BLCA	MIR3155A →	+0.368	+2.933	<.001	.006	3	2
BLCA	MIR3684 →	+0.521	+2.933	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,918 associations by consensus.

Exploration

DDX42 survival (RNA) · tumor vs normal (RNA) · all DDX42 data types