DDX41

Across TCGA patient cohorts, DDX41 protein abundance is significantly associated with the RNA expression of many other genes, with 15,536 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX41-associated genes across cancer lineages are HROB, DKC1, and KIF4A. Each is linked with DDX41 in more than 8 cancer types. Because this analysis shows association rather than direction, both DDX41-to-partner and partner-to-DDX41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX41 versus HROB in UCEC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX41→partner) and Y-score (partner→DDX41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HROB →	+0.885	+0.195	<.001	<.001	3	9
UCEC	DKC1 →	+0.934	+0.287	<.001	<.001	3	9
UCEC	KIF4A →	+1.190	+0.192	<.001	<.001	3	9
UCEC	CENPI →	+0.937	+0.257	<.001	<.001	3	8
BRCA	FOXM1 →	+1.288	+0.252	<.001	<.001	3	8
UCEC	CDC20 →	+1.906	+0.262	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,536 associations by consensus.

DDX41 vs HROB — UCEC

Explore this scatter interactively →