DDX3P3

Across TCGA pan-cancer cohorts, DDX3P3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of DDX3P3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where DDX3P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DDX3P3 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, HNSC, and THCA are the cancer types where DDX3P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DDX3P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.118	<.001	5	view →
HNSC	All	II,III,IV	+0.010	.003	4	view →
THCA	All	All	−0.011	.002	3	view →
STAD	Male	II,III,IV	+0.043	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

DDX3P3–COAD

Open the COAD breakdown →