Across TCGA pan-cancer cohorts, DDX39B mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DDX39B data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DDX39B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DDX39B expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and UCEC are the cancer types where DDX39B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	1.000	0.351	.006	15	view →
CCRCC	OS	Quartile	III,IV	0.904	0.523	.027	5	view →
UCEC	OS	Tertile	II,III,IV	0.612	1.000	.037	4	view →
PDAC	OS	Tertile	III,IV	0.632	0.322	.013	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: DDX39B tumor-vs-normal RNA expression · all DDX39B data types