Across TCGA patient cohorts, DDX39B protein abundance is significantly associated with the RNA expression of many other genes, with 12,296 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDX39B-associated genes across cancer lineages are SFPQ, CYTIP, and JAML. Each is linked with DDX39B in more than 5 cancer types. Because this analysis shows association rather than direction, both DDX39B-to-partner and partner-to-DDX39B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39B→partner) and Y-score (partner→DDX39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SFPQ →	+0.441	+0.235	<.001	<.001	3	6
UCEC	CYTIP →	-1.039	-0.229	<.001	<.001	3	5
LSCC	JAML →	-0.734	-0.184	.002	.003	3	5
LSCC	ZBTB12 →	+0.907	+0.269	<.001	<.001	3	5
LSCC	RPP21 →	+0.448	+0.212	<.001	<.001	3	5
GBM	BIN2 →	-0.695	-0.222	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,296 associations by consensus.

Exploration

DDX39B survival (RNA) · tumor vs normal (RNA) · all DDX39B data types