Across TCGA patient cohorts, DDX39B mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX39B-associated genes across cancer lineages are eIF4G, PDCD4, and STAT3_pY705. Each is linked with DDX39B in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX39B-to-partner and partner-to-DDX39B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39B→partner) and Y-score (partner→DDX39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.271	+2.999	.030	.035	3	2
UCEC	PDCD4 →	-0.584	-2.449	.001	.019	3	2
UCEC	STAT3_pY705 →	-0.563	-3.087	<.001	<.001	3	2
UCEC	ASNS →	+0.444	+3.321	.002	.010	3	2
UCEC	4E-BP1 →	+0.271	+2.199	.012	.033	3	2
UCEC	eIF4E →	+0.172	+3.013	.042	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

DDX39B survival (RNA) · tumor vs normal (RNA) · all DDX39B data types