Across TCGA cell cohorts, DDX39B mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX39B-associated genes across cancer lineages are HCN4, KSR2, and C8A. Each is linked with DDX39B in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX39B-to-partner and partner-to-DDX39B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39B→partner) and Y-score (partner→DDX39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HCN4 →	+0.160	+3.678	<.001	.002	3	2
BLOOD_Leukemia	KSR2 →	+0.373	+3.540	<.001	.005	3	2
SKIN	C8A →	+0.010	+5.022	<.001	.002	3	1
SKIN	UTF1 →	+0.015	+5.022	<.001	.002	3	1
SKIN	OR10AC1 →	+0.019	+4.273	.001	.006	3	1
SKIN	OR52E1 →	+0.081	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

DDX39B survival (RNA) · tumor vs normal (RNA) · all DDX39B data types