Across TCGA cell cohorts, DDX39B mutation is significantly associated with the mutation status of many other genes, with 5,191 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX39B-associated genes across cancer lineages are PI4KB, NIPBL, and RANBP17. Each is linked with DDX39B in more than 3 cancer types. Because this analysis shows association rather than direction, both DDX39B-to-partner and partner-to-DDX39B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39B→partner) and Y-score (partner→DDX39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PI4KB →	+5.584	+5.014	.003	.003	1	4
BLOOD_Leukemia	NIPBL →	+3.176	+3.078	.002	.002	1	4
BLOOD_Lymphoma	RANBP17 →	+3.584	+4.922	.001	.001	1	4
BLOOD_Lymphoma	SCAF8 →	+4.584	+4.584	.007	.007	1	4
BLOOD_Leukemia	UPF1 →	+2.913	+2.913	.003	.003	1	4
BLOOD_Lymphoma	FZD7 →	+4.584	+4.584	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,191 associations by consensus.

Exploration

DDX39B survival (RNA) · tumor vs normal (RNA) · all DDX39B data types