Across TCGA pan-cancer cohorts, DDX39AP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of DDX39AP1’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where DDX39AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DDX39AP1 is over-expressed in tumor.

ESCA and LUAD are the cancer types where DDX39AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DDX39AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+0.050	.037	2	view →
LUAD	Male	All	+0.018	.038	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: DDX39AP1 RNA expression & survival · all DDX39AP1 data types