DDX39A

Across TCGA patient cohorts, DDX39A protein abundance is significantly associated with the protein abundance of many other proteins, with 27,605 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX39A-associated proteins across cancer lineages are AKAP8, SF3B1, and U2SURP. Each is linked with DDX39A in more than 9 cancer types. Because this analysis shows association rather than direction, both DDX39A-to-partner and partner-to-DDX39A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX39A versus AKAP8 in LSCC, with a Pearson correlation of 0.77.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39A→partner) and Y-score (partner→DDX39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKAP8 →	+0.393	+0.463	<.001	<.001	3	10
GBM	SF3B1 →	+0.280	+0.397	<.001	<.001	3	10
LSCC	U2SURP →	+0.269	+0.352	<.001	<.001	3	10
GBM	DNMT1 →	+0.482	+0.402	<.001	<.001	3	10
LSCC	FEN1 →	+0.533	+0.406	<.001	<.001	3	10
GBM	NASP →	+0.560	+0.332	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,605 associations by consensus.

DDX39A vs AKAP8 — LSCC

Explore this scatter interactively →