DDX39A

Across TCGA cell cohorts, DDX39A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,184 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DDX39A-associated GO terms across cancer lineages are Positive regulation of nuclear cell cycle DNA replication, Mitotic chromosome condensation, and DNA-templated DNA replication. Each is linked with DDX39A in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX39A-to-partner and partner-to-DDX39A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of nuclear cell cycle DNA replication grouped by DDX39A-low versus DDX39A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39A→partner) and Y-score (partner→DDX39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of nuclear cell cycle DNA replication →	+0.136	+0.811	<.001	<.001	3	19
OESOPHAGUS	Mitotic chromosome condensation →	+0.227	+1.014	<.001	<.001	3	19
PANCREAS	DNA-templated DNA replication →	+0.116	+0.966	<.001	<.001	3	17
OESOPHAGUS	Regulation of DNA-templated DNA replication →	+0.112	+0.803	<.001	<.001	3	17
OESOPHAGUS	DNA replication →	+0.092	+0.710	.005	.002	3	17
BLOOD_Myeloma	DNA replication checkpoint signaling →	+0.198	+0.992	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,184 associations by consensus.

Positive regulation of nuclear cell cycle DNA replication by DDX39A expression — OESOPHAGUS

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