DDX39A

Across TCGA cell cohorts, DDX39A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX39A-associated genes across cancer lineages are IQCF5, AVP, and OR10Q1. Each is linked with DDX39A in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX39A-to-partner and partner-to-DDX39A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF5 grouped by DDX39A-low versus DDX39A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39A→partner) and Y-score (partner→DDX39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1
LARGE_INTESTINE	AVP →	+0.068	+4.217	<.001	.001	3	1
LARGE_INTESTINE	OR10Q1 →	+0.110	+3.920	.001	.005	3	1
LARGE_INTESTINE	SPINK9 →	+0.338	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IQCF5 by DDX39A expression — BLOOD_Leukemia

Explore this box plot interactively →