DDX28

Across TCGA patient cohorts, DDX28 protein abundance is significantly associated with the RNA expression of many other genes, with 16,030 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX28-associated genes across cancer lineages are WIPF1, STARD9, and PRICKLE2. Each is linked with DDX28 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDX28-to-partner and partner-to-DDX28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX28 versus WIPF1 in OV, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX28→partner) and Y-score (partner→DDX28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WIPF1 →	-0.874	-0.310	.003	.001	2	8
OV	STARD9 →	-0.634	-0.259	.002	.007	3	7
BRCA	PRICKLE2 →	-0.744	-0.362	.002	<.001	3	7
BRCA	CSGALNACT2 →	-0.690	-0.414	<.001	<.001	3	7
OV	VGLL3 →	-1.148	-0.393	<.001	<.001	3	7
LSCC	TNFSF12 →	-0.633	-0.557	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,030 associations by consensus.

DDX28 vs WIPF1 — OV

Explore this scatter interactively →