DDX28

Across TCGA cell cohorts, DDX28 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,801 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DDX28-associated GO terms across cancer lineages are Mitochondrial large ribosomal subunit assembly, Mitochondrial ribosome assembly, and 'de novo' UMP biosynthetic process. Each is linked with DDX28 in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX28-to-partner and partner-to-DDX28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial large ribosomal subunit assembly grouped by DDX28-low versus DDX28-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX28→partner) and Y-score (partner→DDX28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial large ribosomal subunit assembly →	+0.167	+1.123	<.001	<.001	3	19
BLOOD_Myeloma	Mitochondrial ribosome assembly →	+0.126	+1.462	<.001	<.001	3	18
LUNG_NSCLC_LUSC	'de novo' UMP biosynthetic process →	+0.122	+0.625	<.001	<.001	3	17
BLOOD_Myeloma	Ribosomal large subunit assembly →	+0.147	+1.338	<.001	<.001	3	17
BLOOD_Myeloma	Ribosome assembly →	+0.123	+1.348	<.001	<.001	3	17
LIVER	Peptidyl-methionine modification →	+0.245	+0.476	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,801 associations by consensus.

Mitochondrial large ribosomal subunit assembly by DDX28 expression — BONE

Explore this box plot interactively →