DDX24

Across TCGA pan-cancer cohorts, DDX24 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DDX24 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DDX24 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DDX24 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

PDAC, LSCC, and UCEC are the cancer types where DDX24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	II,III,IV	0.830	1.000	.001	18	view →
LSCC	DFS	Quartile	II,III,IV	0.939	0.586	.012	9	view →
UCEC	DFS	Tertile	All	0.845	0.975	.025	6	view →
OV	DFS	Median	All	0.646	0.929	.036	4	view →
HNSC	OS	Quartile	All	0.827	0.937	.020	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DDX24–PDAC (OS)

Open the PDAC breakdown →