DDX19B

Across TCGA patient cohorts, DDX19B mutation is significantly associated with the RNA expression of many other genes, with 1,386 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX19B-associated genes across cancer lineages are RNU6-358P, MRPL41, and RNU6-633P. Each is linked with DDX19B in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX19B-to-partner and partner-to-DDX19B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-358P grouped by DDX19B-low versus DDX19B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX19B→partner) and Y-score (partner→DDX19B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-358P →	+0.576	+3.993	<.001	.005	3	2
UCEC	MRPL41 →	+0.547	+3.098	.005	<.001	3	2
UCEC	RNU6-633P →	+0.382	+2.085	<.001	.004	3	2
UCEC	CNN2P4 →	+0.689	+2.532	<.001	.009	3	2
UCEC	RNF167 →	+0.475	+2.415	<.001	.003	3	2
UCEC	EMC6 →	+0.868	+2.415	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,386 associations by consensus.

RNU6-358P by DDX19B expression — SKCM

Explore this box plot interactively →