DDX19A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DDX19A mutation is significantly associated with the RNA expression of many other genes, with 2,976 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX19A-associated genes across cancer lineages are PSAT1P4, RNU6-782P, and LINC02040. Each is linked with DDX19A in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX19A-to-partner and partner-to-DDX19A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSAT1P4 grouped by DDX19A-low versus DDX19A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX19A→partner) and Y-score (partner→DDX19A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPSAT1P4 →+0.127+1.837.002.00333
LGGRNU6-782P →+0.396+6.632<.001.00132
CESCLINC02040 →+0.151+5.539<.001.00432
CESCRN7SL398P →+0.135+5.306<.001.00632
CESCLSP1P1 →+0.266+5.539<.001.00432
COADMIR1224 →+0.374+4.332<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,976 associations by consensus.

PSAT1P4 by DDX19A expression — UCEC

Box plot of PSAT1P4 in DDX19A-low vs DDX19A-high samples in UCEC.

Explore this box plot interactively →

Exploration