DDX19A

Across TCGA cell cohorts, DDX19A mutation is significantly associated with the drug of many other genes, with 59 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX19A-associated genes across cancer lineages are GSK1904529A, PAK_5339, and Teniposide. Each is linked with DDX19A in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX19A-to-partner and partner-to-DDX19A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK1904529A grouped by DDX19A-low versus DDX19A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX19A→partner) and Y-score (partner→DDX19A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK1904529A →	+0.502	+2.678	.002	.037	3	1
LARGE_INTESTINE	PAK_5339 →	+0.398	+2.678	.006	.037	3	1
LARGE_INTESTINE	Teniposide →	+0.556	+2.649	.037	.046	3	1
LARGE_INTESTINE	Savolitinib →	+0.444	+2.777	.012	.038	3	1
LARGE_INTESTINE	BX-912 →	+0.591	+2.652	.043	.045	3	1
LARGE_INTESTINE	Fedratinib →	+0.539	+2.652	.040	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

GSK1904529A by DDX19A expression — LARGE_INTESTINE

Explore this box plot interactively →