DDX18P4

Across TCGA pan-cancer cohorts, DDX18P4 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated DDX18P4 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher DDX18P4 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DDX18P4 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BLCA show a favorable association.

LUSC, BLCA, and HNSC are the cancer types where DDX18P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	All	0.538	0.359	.003	66	view →
BLCA	OS	Tertile	All	0.939	0.651	.023	39	view →
HNSC	OS	Tertile	IV	0.709	0.566	.019	38	view →
MESO	DFS	Tertile	IV	0.071	0.359	.009	36	view →
LUAD	DFS	Tertile	All	0.571	0.247	<.001	30	view →
COAD	DFS	Tertile	IV	0.179	0.545	.012	18	view →
KIRP	OS	Tertile	All	1.000	0.668	.016	18	view →
ACC	OS	Tertile	All	0.147	0.685	.018	18	view →
KIRC	DFS	Tertile	IV	0.225	0.533	.012	18	view →
ESCA	OS	Tertile	IV	0.856	0.219	.024	12	view →
PRAD	OS	Tertile	All	0.934	0.993	<.001	12	view →
READ	OS	Tertile	IV	0.468	0.937	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

DDX18P4–LUSC (DFS)

Open the LUSC breakdown →