DDX17

Across TCGA patient cohorts, DDX17 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,290 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DDX17-associated proteins across cancer lineages are XRCC5, NRBF2, and TRIM3_S7. Each is linked with DDX17 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDX17-to-partner and partner-to-DDX17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX17 versus XRCC5 in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX17→partner) and Y-score (partner→DDX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	XRCC5 →	+0.200	+0.406	<.001	<.001	3	6
CCRCC	NRBF2 →	-0.366	-0.236	<.001	.001	3	6
BRCA	TRIM3_S7 →	+0.783	+0.781	<.001	<.001	3	5
OV	PPIF →	-0.601	-0.749	<.001	<.001	3	5
GBM	XRCC6 →	+0.269	+0.392	<.001	<.001	3	5
OV	ESD →	+0.456	+0.858	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,290 associations by consensus.

DDX17 vs XRCC5 — GBM

Explore this scatter interactively →