DDX17

Across TCGA cell cohorts, DDX17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,914 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DDX17-associated GO terms across cancer lineages are Regulation of organelle assembly, Negative regulation of chromosome condensation, and Cytoskeleton-dependent intracellular transport. Each is linked with DDX17 in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX17-to-partner and partner-to-DDX17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by DDX17-low versus DDX17-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX17→partner) and Y-score (partner→DDX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of organelle assembly →	+0.045	+0.932	<.001	<.001	3	19
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.192	+1.081	<.001	<.001	3	17
KIDNEY	Cytoskeleton-dependent intracellular transport →	+0.041	+0.882	.002	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.136	+1.323	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.143	+1.308	<.001	<.001	3	17
STOMACH	Protein sumoylation →	+0.090	+0.889	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,914 associations by consensus.

Regulation of organelle assembly by DDX17 expression — PANCREAS

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