DDX11L9

Across TCGA pan-cancer cohorts, DDX11L9 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DDX11L9’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where DDX11L9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DDX11L9 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

BRCA, COAD, and THCA are the cancer types where DDX11L9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DDX11L9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.011	.003	4	view →
COAD	Female	All	−0.008	.039	1	view →
THCA	Female	All	−0.004	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

DDX11L9–BRCA

Open the BRCA breakdown →