DDX11L10

Across TCGA pan-cancer cohorts, DDX11L10 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated DDX11L10 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher DDX11L10 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DDX11L10 expression acts as an unfavorable survival marker, although some lineages such as BLCA and MESO show a favorable association.

BLCA, STAD, and CESC are the cancer types where DDX11L10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Quartile	II,III,IV	0.709	0.517	<.001	85	view →
STAD	DFS	Quartile	II,III,IV	0.472	0.694	.002	42	view →
CESC	DFS	Median	All	0.667	0.802	.004	28	view →
BRCA	OS	Tertile	All	0.950	0.979	.002	15	view →
MESO	OS	Tertile	IV	0.918	0.420	.003	15	view →
ACC	DFS	Tertile	All	0.203	0.624	.021	14	view →
PCPG	DFS	Median	All	0.936	0.826	.019	9	view →
UCEC	DFS	Tertile	All	0.868	0.908	.018	8	view →
ESCA	DFS	Quartile	All	0.369	0.535	.029	7	view →
KIRC	OS	Median	II,III,IV	0.652	0.732	.022	7	view →
SKCM	OS	Quartile	IV	0.276	0.747	.016	6	view →
PAAD	OS	Tertile	III,IV	0.723	1.000	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

DDX11L10–BLCA (OS)

Open the BLCA breakdown →