DDX11

Across TCGA patient cohorts, DDX11 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,623 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDX11-associated proteins across cancer lineages are PRIM2, NIP7, and NOL11. Each is linked with DDX11 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDX11-to-partner and partner-to-DDX11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX11 versus PRIM2 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX11→partner) and Y-score (partner→DDX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRIM2 →	+0.592	+0.765	<.001	<.001	3	8
BRCA	NIP7 →	+0.467	+0.540	<.001	<.001	3	7
LSCC	NOL11 →	+0.272	+0.534	.002	.001	3	7
LSCC	UBE2T →	+0.679	+0.734	<.001	<.001	3	7
LUAD	UNG_S23 →	+1.002	+0.968	<.001	<.001	3	7
HNSC	DDX47 →	+0.449	+1.030	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,623 associations by consensus.

DDX11 vs PRIM2 — GBM

Explore this scatter interactively →