DDX11

Across TCGA patient cohorts, DDX11 protein abundance is significantly associated with the RNA expression of many other genes, with 8,440 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX11-associated genes across cancer lineages are CENPA, KIF14, and DLGAP5. Each is linked with DDX11 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDX11-to-partner and partner-to-DDX11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX11 versus CENPA in LUAD, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX11→partner) and Y-score (partner→DDX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CENPA →	+1.023	+0.573	<.001	<.001	3	6
PDAC	KIF14 →	+1.163	+0.590	<.001	.004	3	6
PDAC	DLGAP5 →	+1.410	+0.641	<.001	.001	3	6
BRCA	KIF11 →	+1.013	+0.759	<.001	<.001	3	6
PDAC	CEP55 →	+1.290	+0.624	<.001	.002	3	6
LSCC	NUF2 →	+1.166	+0.629	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,440 associations by consensus.

DDX11 vs CENPA — LUAD

Explore this scatter interactively →