DDX1

Across TCGA patient cohorts, DDX1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,855 significant associations in total. ACC shows the largest number of these associations.

The most reproducible DDX1-associated genes across cancer lineages are HMGXB4, RNMT, and USP10. Each is linked with DDX1 in more than 33 cancer types. Because this analysis shows association rather than direction, both DDX1-to-partner and partner-to-DDX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX1 versus HMGXB4 in DLBC, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX1→partner) and Y-score (partner→DDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	HMGXB4 →	+1.337	+0.665	<.001	<.001	3	34
UVM	RNMT →	+1.386	+1.457	<.001	<.001	3	34
KICH	USP10 →	+1.007	+1.172	<.001	<.001	3	34
UVM	RPS6KB1 →	+1.402	+1.503	<.001	<.001	3	34
UVM	INTS2 →	+1.267	+1.432	<.001	<.001	3	34
UVM	NAA25 →	+1.223	+1.496	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,855 associations by consensus.

DDX1 vs HMGXB4 — DLBC

Explore this scatter interactively →