DDX1

Across TCGA patient cohorts, DDX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,171 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX1-associated proteins across cancer lineages are YWHAQ, ZNF638, and ZNF687. Each is linked with DDX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDX1-to-partner and partner-to-DDX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX1 versus YWHAQ in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX1→partner) and Y-score (partner→DDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YWHAQ →	+0.467	+0.529	<.001	<.001	3	6
LSCC	ZNF638 →	+0.288	+0.562	<.001	<.001	3	6
LSCC	ZNF687 →	+0.333	+0.473	<.001	<.001	3	6
GBM	PPM1G →	+0.531	+0.293	<.001	<.001	3	6
GBM	MSH2 →	+0.660	+0.324	<.001	<.001	3	6
UCEC	PRRC2C →	+0.219	+0.452	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,171 associations by consensus.

DDX1 vs YWHAQ — OV

Explore this scatter interactively →